Comparative study of uterotonic agents in the prevention of post partum haemorrhage following vaginal delivery
Phase 4
Recruiting
- Conditions
- Health Condition 1: O720- Third-stage hemorrhage
- Registration Number
- CTRI/2023/09/057333
- Lead Sponsor
- Ramaiah medical college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
(1) at or beyond 28 gestational weeks; (2) 18–45 years old; (2) at least one risk factor for developing atony.
Exclusion Criteria
Participants with cardiovascular disorders, hepatic or renal disease, epilepsy, known allergies to oxytocin or carbetocin.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The aim of the study is to compare the effects of carbetocin with those of oxytocin in several dosing regimens for the prevention of uterine atony in patients undergoing full term vaginal delivery. The outcome is assessed in terms of blood loss, need for additional uterotonic agents, fall in blood pressure, side effects of the drug Carbetocin if any <br/ ><br>Timepoint: Outcome is assessed immediately after delivery and 12 hours, 24 hours after delivery.
- Secondary Outcome Measures
Name Time Method This study is aimed at comparing the effects of carbetocin vs oxytocin in prevention of postpartum hemorrhage following vaginal delivery in terms of: <br/ ><br>Secondary outcomes - <br/ ><br>Fall in hb <br/ ><br>Requirement of additional uterotonic agents <br/ ><br>Adverse effects <br/ ><br>Need for blood transfusionTimepoint: Outcome is assessed immediately after delivery, 12 hours & 24 hours