comparison of intravenous dexmedetomidine versus magnesium sulphate for controlled hypotension in functional endoscopic sinus surgery

Not yet recruiting

• Conditions: Chronic rhinitis,

• Registration Number: CTRI/2022/05/042615
• Lead Sponsor: Dr Rashmi Thakur

Brief Summary

**This is a interventional prospective  randomized double-blind study of comparison between magnesium sulphate versus dexmedetomidine for controlled hypotension in FESS between age group 18 to 60yrs with ASA Physical status I&II with patients undergoing Functional Endoscopic Sinus Surgery. It will be conducted at single center in India. Primary outcome measures will be Quality of surgical field as accessed by average category scale in terms of bleeding and dryness and secondary outcome measures will be amount of blood loss and surgeon’s satisfaction score regarding bloodless field and side effects and complications.**

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-05-13
• Study Start: 2022-05-20

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 92

Inclusion Criteria

• ASA Physical status – l and ll 2.Patients undergoing functional endoscopic sinus surgery 3.
• Weight 55-85 kg.

Exclusion Criteria

• Patient’s refusal 2.
• Hypersensitivity to study drugs 3.
• Patients with recurrent sinus surgery 4.
• patients with coagulopathies 6.
• systemic hypertension 7.
• Sinus bradycardia 8.Cardiovascular diseases, Renal diseases, Central nervous system diseases, and Hepatic diseases 9.
• Novel corona virus positive 10.
• Known history of substance abuse or alcohol abuse.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of surgical field as accessed by average category scale in terms of bleeding and dryness	intra operative period

Secondary Outcome Measures

Name	Time	Method
Amount of blood loss	Surgeons satisfaction score regarding bloodless field

Trial Locations

Locations (1)

Dr Bhimrao Ambedkar Memorial Hospital Raipur; 🇮🇳 Raipur, CHHATTISGARH, India

Dr Bhimrao Ambedkar Memorial Hospital Raipur

🇮🇳Raipur, CHHATTISGARH, India

DR Kaviyarasan

Principal investigator

6381805624

kaviyarasanarumugam1927@gmail.com