B-lines Score Derived From Lung Ultrasonography as a Noninvasive Indicator for the Systemic Volumetric Load During TURP. A Prospective Observational Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 125
- 试验地点
- 1
- 主要终点
- Predictive ability of the LUS using B-lines for the presence of systemic volume overload in patients undergoing endoscopic TURP
研究概览
简要总结
Lung Ultrasonography score (LUS) using B-lines is a noninvasive, reliable and promising method for determining the extravascular lung water (EVLW). This was previously evaluated by trans-pulmonary thermodilution technique.
The transurethral resection of the prostate syndrome (TURP-S) is a potentially life-threatening complication of the TURP surgery and timely diagnosis of TURP-S is crucial for rapid detection and optimized treatment.
This observational study is designed to investigate the use of LUS using B-lines as a bed-side, simple, and non-invasive indicator for predication of the presence of systemic volume overload in patients undergoing endoscopic TURP.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 60 Years 至 90 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Age ≥ 60 years.
- •American Society of Anesthesiologists Classification (ASA ) I, II, and III.
- •Full conscious patients.
排除标准
- •Patient refusal.
- •Who known allergic or hypersensitivity to any drug used in the study (local anesthesia).
- •Coagulopathy (history of bleeding disorders), or patients on anticoagulant drugs, with (platelets <50,000 International Normalised Ratio( INR)>1.5).
- •Patients have renal dysfunction patients with creatinine ≥
- •Patients have uncontrolled cardiac diseases (IHD, (congestive heart failure (CHF), pulmonary hypertension and valvular diseases).
- •Abdominal ascites.
- •Patients with local infection at the site of local anesthetic injection.
- •Failed spinal anesthesia.
- •Timing not exceed 90 min.
- •Any patient with lung ultrasound examination at T 0 ≥ 3 B-lines will be excluded from the study.
结局指标
主要结局
Predictive ability of the LUS using B-lines for the presence of systemic volume overload in patients undergoing endoscopic TURP
时间窗: From the preoperative period (T0) to 60 Minutes postoperative (T PACU)
using ultrasound
次要结局
- Correlation between the absolute value of LUS, Caval-Aorta index .(From the preoperative period (T0) to 60 Minutes postoperative (T PACU))
- Predictive ability of the Caval-Aorta index as predictors of systemic volume overload in patients undergoing endoscopic TURP.(From the preoperative period (T0) to 60 Minutes postoperative (T PACU))
- Correlation between the relative changes of the LUS and Caval-Aorta index(From the preoperative period (T0) to 60 Minutes postoperative (T PACU))
研究者
Dalia Saad Abd-El Kader
assistant professor
Kasr El Aini Hospital