urine sodium and potassium concentration to predict kidney failure in patients of severe infection in IC
Not Applicable
Completed
- Conditions
- Health Condition 1: B999- Unspecified infectious disease
- Registration Number
- CTRI/2022/03/041334
- Lead Sponsor
- Department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 111
Inclusion Criteria
>18yrs of age with clinically suspected sepsis
Exclusion Criteria
1) pre existing AKI or CKD
2) diuretic exposure
3) patients without indwelling catheter
4) surgery or trauma involving kidneys
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess if 2 hour urinary potassium levels can predict development of AKI in sepsis patients <br/ ><br>Timepoint: 2hour urine electrolyte concentration is measured at a single point after onset of sepsis. <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1)To assess correlation between urinary excretion of potassium and urinary excretion of sodium and measured 2hour creatinine clearance. <br/ ><br>2)To assess correlation between urinary excretion of sodium and measured 2hour creatinine clearance. <br/ ><br>3)To assess the ability of the ratio of urinary potassium to urinary creatinine in predicting AKI. <br/ ><br>4)To assess the ability of 2hour urinary potassium levels and the ratio of urinary potassium to urinary creatinine in predicting requirement of RRT. <br/ ><br>5)To assess the ability of fractional excretion of sodium and fractional excretion of potassium in predicting AKI <br/ ><br> <br/ ><br>Timepoint: Daily followup of creatinine and urine output to determine AKI