The effectiveness of intravenous dexmeditomidine versus lignocaine on perioperative haemodynamics in patients undergoing laparoscopic cholecystectomy
Phase 4
- Conditions
- Health Condition 1: K810- Acute cholecystitis
- Registration Number
- CTRI/2021/07/034595
- Lead Sponsor
- OT APPLICABLE
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American Society of Anaesthesiologists physical status I,II,III
2)Patients with age :20 TO 60 Years.
3) BMI <=30 kg/m2
4)Patients undergoing elective laparoscopic cholecystectomy (non malignant) .
Exclusion Criteria
1)Patients refusal
2)Patients with uncontrolled cardio respiratory, renal, hepatic or endocrine disease
3)Conversion of laparoscopic to open cholecystectomy
4)Patients with drains placed insitu.
5)Patients who are unable to perform VAS scale.
6)Surgical time exceeding 150 min.
7)Pregnant and lactating women.
8)Patients who are on Beta adrenergic blocker therapy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the attenuation of blood pressure and heart rate response to pneumo peritoneum in patients undergoing laparoscopic cholecystectomyTimepoint: the first requirement of analgesic dose within 24 hours
- Secondary Outcome Measures
Name Time Method To compare the post operative sedation score between two groups <br/ ><br>To assess and compare the Time to first request for analgesia post operatively.-defined as whenever the patient complains of pain or when visual analogue score <br/ ><br>Number of propofol boluses required peri operatively. <br/ ><br>Number of episodes of hypertension and hypotension peri operatively. <br/ ><br>Number of doses of atropine, ephedrine, phenyl ephrine required intra operatively. <br/ ><br> <br/ ><br>Timepoint: 15,30,60minutes,2,3,4hours