se of Magnesium Sulfate to control postoperative pain in patients undergoing uterus removal surgery

Not Applicable

• Conditions: Women under the age of 65; Physical State I to III of the American Society of Anesthesiologists (ASA); who are candidates for non-oncologic abdominal hysterectomy; C04.557.450.590.540; C13.351.500.852.691.449; C23.550.568.750; D25.9

• Registration Number: RBR-7b5x5k
• Lead Sponsor: Hospital Geral de Cuiabá

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-04-20
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women under the age of 65; classified in Physical State I to III of the American Society of Anesthesiology; who are candidates for non-oncologic abdominal hysterectomy

Exclusion Criteria

Age under 18 years; body mass index less than 40; renal dysfunction; neuropathy or myopathy; known hypersensitivity to magnesium sulfate or to drugs used according to the protocol; previous treatment with calcium channel blockers; all types of heart block; opiate addiction; patient's refusal to participate in the study; contraindication to spinal anesthesia

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Decreased postoperative pain by at least 30% assessed using the 0-10 cm Visual Analogue Scale (VAS), where one end of the line is written no pain” and the other worst pain imaginable”. This assessment will be performed at rest and during the change from the supine position to the sitting position in the hospital bed at six and 24 hours after the operation.

Secondary Outcome Measures

Name	Time	Method
The delay in administering the first analgesic rescue with tramadol, using the Kaplan-Meir curve in the first 24 hours after surgery.;Reduction in the incidence of nausea (subjective feeling unpleasant to the imminence of vomiting) and vomiting (rapid and forced expulsion of gastric contents through the mouth, caused by a strong and sustained contraction of the chest and abdominal wall muscles) in 24 hours postoperatively .;Decreased consumption of tramadol in mg to treat pain in the first 24 hours after surgery.