Circadian Rhythm in Anti-Epileptic Drugs
- Conditions
- epilepsy10039911
- Registration Number
- NL-OMON33832
- Lead Sponsor
- Christelijke Vereniging voor de Verpleging van Lijders aan Epilepsie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
Diagnosed epilepsy
Age: 18 to 65 years
Capable of understanding the study and giving informed consent
>= 2 and <= 30 seizures per month
A chronotype other than *Neither morning nor eveningtype* according to the morningness/eveningsness questionnaire
Exclusion Criteria
Anamnestic history of circadian rhythm disorders, such as shift work or transmeridian travelling in the past month and/ or during the study
Change of therapy (AED/ combination/ dosage/ frequency) two months prior to and during the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Time to nth seizure after adjusting administration times</p><br>
- Secondary Outcome Measures
Name Time Method <p>Quality of Life (measured by the Qolie-31 (Quality of Life in Epilepsy, version<br /><br>1.0 in Dutch))<br /><br>Adverse Drug Reaction (measured by The Stepped Care Adverse Drug Reaction List<br /><br>(in Dutch, by Prof. Dr. Aldenkamp))</p><br>