Dapsone gel in the treatment of papulopustular rosacea
Not Applicable
- Conditions
- Papulopustular Rosacea.Other rosacea
- Registration Number
- IRCT2014010516079N1
- Lead Sponsor
- Vice chancellor for research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 56
Inclusion Criteria
age between 18 and 55, patients with papulopustular facial rosacea, negative history of using topical steroid or retinoic acid during last month, negative history of using oral anti-inflammatory agents and oral retinoic acids during last month and last 180 days respectively
Exclusion criteria: Pregnancy or lactation, any history of G6PD deficiency, any history of hypersensitivity to dapsone or metronidazole, any history of oral cotrimoxasole treatment
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rasoacea papulopustular lesions. Timepoint: Baseline, week 4, week 8, week 12. Method of measurement: Number of inflammatory lesions, Visual analogue score (VAS.) and Investigator’s global assessment scores (IGA.).
- Secondary Outcome Measures
Name Time Method Side effects of drug. Timepoint: Every 4 weeks. Method of measurement: clinical evaluation-laboratory test.