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临床试验/CTRI/2026/03/105713
CTRI/2026/03/105713尚未招募不适用

Inflammatory Phenotypes in Acute Respiratory Distress Syndrome Incidence and Association with Morbidity and Mortality

Grant Medical Foundation Ruby Hall Clinic1 个研究点 分布在 1 个国家目标入组 88 人开始时间: 2026年3月20日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
88
试验地点
1

研究概览

简要总结

Rationale of the study

Understanding the incidence of inflammatory phenotypes in ARDS patients and their association with clinical outcomes could

Improve risk stratification by identifying patients at higher risk of mortality or complications.

Guide targeted therapies tailored to the patients inflammatory profile potentially optimizing treatment efficacy.

Provide insights into pathophysiology and aid future research on personalized management strategies for ARDS.

Limited data exist on their prevalence and impact in Indian ICUs making this study essential.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • 1 Patients with ARDS 2 Patients within 7 days from invasion or exacerbation of respiratory symptoms or acute onset of ARDS 3 Patients with bilateral opacities not fully explained by effusions 4 Patients with respiratory failure not fully explained by cardiac failure 5 PF ratio less than 300mmHg with PEEP at least 5cm H2O 6 ARDA diagnosis within 48 hours.

排除标准

  • 1 Patients with congestive cardiac failure 2 Patients with liver failure 3 Patients with chronic renal failure requiring renal dialysis therapy 4 Patients with burns more than 20 percent of total body surface area 5 Patients with chronic inflammatory or autoimmune disease 6 Pregnant or lactating women 7 Patients with palliative care.

研究者

发起方
Grant Medical Foundation Ruby Hall Clinic
申办方类型
Other [Trust Hospital]
责任方
Principal Investigator
主要研究者

Dr Kapil Zirpe

Grant Medical Foundation Ruby Hall Clinic

研究点 (1)

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