Periodontal Health and Quality of Life in Psoriasis Patients

Completed

• Conditions: Psoriasis; Periodontal Diseases

• Registration Number: NCT07154420
• Lead Sponsor: Saglik Bilimleri Universitesi

Brief Summary

This study aims to evaluate the relationship between psoriasis, a chronic inflammatory skin disease, and oral health. We will assess the periodontal (gum) condition of patients with psoriasis and examine how it affects their quality of life. A group of psoriasis patients and a control group without psoriasis will undergo oral examinations and complete a short questionnaire. The goal is to better understand whether psoriasis has an impact on gum health and daily well-being.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-04-20
• Primary Completion: 2025-07-20
• Study Completion: 2025-07-20
• Status Verified: 2025-08
• Study First Submitted: 2025-08-19
• Study First Submitted QC: 2025-08-26
• Last Update Submitted: 2025-08-26
• Study First Posted: 2025-09-04
• Last Update Posted: 2025-09-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 226

Inclusion Criteria

• Participants aged 18 to 65 years
• Clinically diagnosed with active psoriasis
• The presence of at least 12 teeth (excluding third molars)
• Absence of contraindications for periodontal clinical examination

Exclusion Criteria

• Other dermatological conditions
• Pregnancy or lactation
• Antibiotic use within the last 3 months
• Chemotherapy or radiotherapy within the last year
• Periodontal treatment within the last 6 months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of oral health-related quality of life in psoriasis patients	Baseline	The Turkish version of the OHIP-14 questionnaire was administered through face-to-face interviews by a single investigator (G.U.), who was blinded to the periodontal status of the participants. The OHIP-14 consists of seven subscales, each including two items: functional limitation, physical pain, psychological discomfort, physical disability, psychological disability, social disability, and handicap. Participants rated the frequency of negative experiences on a five-point Likert scale (0 = never, 1 = rarely, 2 = occasionally, 3 = quite often, 4 = very often). The total score ranges from 0 to 56, with higher scores reflecting a greater negative impact on oral health-related quality of life

Secondary Outcome Measures

Name	Time	Method
Evaluation of dermatology-specific quality of life in psoriasis patients	Baseline	Psoriasis Quality of Life Questionnaire (PQLQ) measures functional limitation, physical discomfort, psychological distress, social maladjustment, and disability. Each item was scored on a Likert-type scale, with higher scores reflecting a greater impact on daily life.

Trial Locations

Locations (1)

Sağlık Bilimleri Üniversitesi; Ankara, Ankara, Turkey (Türkiye)