The Role of Serotonin in Intensive Care Patients

Recruiting

• Conditions: Sepsis; Septic Shock; Cardiac Arrest With Successful Resuscitation; Multiple Trauma

• Registration Number: NCT05386199
• Lead Sponsor: Oslo University Hospital

Brief Summary

Sepsis, cardiac arrest and multiple trauma are potentially life-threatening conditions and common reasons for intensive care unit (ICU) admission. The aim of this study is to investigate the role of the signaling substance serotonin in blood in these conditions.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-05
• Study First Submitted: 2022-05-06
• Study First Submitted QC: 2022-05-18
• Study First Posted: 2022-05-23
• Study Start: 2022-05-25
• Last Update Submitted: 2022-05-27
• Last Update Posted: 2022-05-31
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
PPP-serotonin	As soon as possible after ICU admission. No more than 3 days after admission.	Serotonin in platelet poor plasma

Secondary Outcome Measures

Name	Time	Method
Platelet serotonin	End of first week at ICU, an average of 5 days after admission.	Serotonin in platelets
PPP-serotonin	End of first week at ICU, an average of 5 days after admission.	Serotonin in platelet poor plasma

Trial Locations

Locations (1)

Oslo University Hospital Ullevål; 🇳🇴 Oslo, Norway