Assessment of lung water in patients with low blood pressure after infectio

Completed

• Conditions: Septic shock; Circulatory System

• Registration Number: ISRCTN11419081
• Lead Sponsor: Phramongkutklao Hospital Foundation Under Her Royal Highness Princess Maha Chakri Sirindhorn Patronage

Brief Summary

2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/30294131

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2014-07-30
• Study Start: 2015-02-04
• Last Update Posted: 5 November 2018

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

1. Age 18 years old or over
2. Septic shock requiring central venous catheterisation and arterial catheterisation for continuous pressure monitoring

Exclusion Criteria

1. Valvular heart disease
2. Pregnancy
3. Acute or history of pulmonary embolism
4. Lung resection surgery
5. Acute respiratory distress syndrome
6. Interstitial lung diseases
7. Mulitilobar pneumonia
8. Pleural diseases

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Best method of lung ultrasound to diagnose pulmonary oedema in patients with septic shock: cutoff point of extravascular water index measured by transpulmonary thermodilution greater than<br>10 mL/kg predicted bodyweight, which is correlated with a pulmonary capillary wedge pressure of greater than 20 mmHg to indicate pulmonary oedema

Secondary Outcome Measures

Name	Time	Method
Cutoff point of total B-line scores to predict extravascular lung water index of 10 mL/kg or more