A pilot study to caluculate AMPA receptors changes in language related areas and its homologous areas with [11C]K-2 PET imaging in stroke-aphasia patients during speech therapy

Abe Hiroki0 个研究点目标入组 8 人开始时间: 2021年1月8日最近更新: 2023年10月17日

适应症

试验速览

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•1. 20 years older and 86 years younger at the registration
•2. Diagnosed as initial symptomatic stroke with aphasia
•3. A Patient who can express his or her intent to participate in this research with written documents by himself or herself. When a patient is unable to write his or her sign due to their aphasia symptom, a substitute who was asked to write his or her sign by the patient can express intents to participate in this research with written documents in stead of the patient.

•1. Patients with Raven's coloured porgressive Matrices's score less than 18
•2. Patients with Brunstrome stage less than 4 in at least one area among fingers, upper limbs and lower limbs
•3. Patients with biochemical examination below ; (a) serum Cr >=2.0 mg/dl, (b) AST >=200 IU/L, (c) ALT >=150 IU/L
•4. Patients with post-stroke epilepsy
•5. Patients who need an administrarion of perampanel
•6. Patients with dialysis
•7. Patients who can not undergo head 3T-MRI
•8. Patients who desire to undergo non invasive brain stimulation therapy

发起方

Abe Hiroki