A pilot study to measure the change of AMPA receptors' densities in striatum due to dopamin deficiency measured with [11C]K-2 PET imaging in Parkinson's disease.

Abe Hiroki0 个研究点目标入组 15 人开始时间: 2021年3月29日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1. 40 years old older and younger than 81 years old at the registration
•2. Diagnosed as clinically established Parkinson's disease with MDS PD criteria 2015.
•3. Underwent DAT SPETC within a year.
•4. Patients who can express intents to participate in this research with written documents.
•A person who decides to participate in this research at his / her own free will can obtain written consent. However, when the consent explanation document cannot be read or written by the disease's symptoms, a witness will give his/her written consent. The witnesses are adults who are not unduly affected by those involved in this study and can take a third-party position. When he/she can not provide informed consent, it is possible to provide written consent with the substitute person's signature. A substitute person is an adult who is equivalent to his / her spouse, parents, compatriots, children, family members living together, or close relatives and can represent the will and interests.

•1. Patients who can not anwser their name, birth date or current month.
•2. Patients who have a history of epilepsy.
•3. Patients with dyalysis.
•4. Patients who can not undergo head 3T-MRI.
•5. Patietnts who underwent non-invasive brain stimulation therapy within a year.
•6. Patients who have symptoms which could not be explained by PD.

发起方

Abe Hiroki