Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hepatic and Renal Dysfunction After Pneumoperitoneum
- Conditions
- Renal Function DisorderHepatic Dysfunction Transient
- Registration Number
- NCT02013596
- Lead Sponsor
- Zhihong LU
- Brief Summary
The purpose of this study is to compare the effect of TEAS pretreatment and treatment on hepatic and renal dysfunction induced by pneumoperitoneum in patients undergoing laparoscopic surgeries.
- Detailed Description
Patients were randomly assigned to three groups, control group and two intervention groups, receiving TEAS before and after general anesthesia induction respectively. TEAS was given through electrodes attached to acupoints. The time for TEAS was 30min. Venous blood samples were collected before and 20min after pneumoperitoneum. Hepatic and renal function index including AST, ALT, ALP, BUN, Cr were measured.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 168
- Age>18yrs,<60yrs；
- ASA 1-2；
- Scheduled for laparoscopic surgery under general anesthesia；
- Informed consented
- Patients with hepatic or renal dysfunction；
- Patients with severe hypertension or cardiac dysfunction；
- Patients with severe pulmonary disease；
- Patients with hemoglobin<100g/L
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Incidence of renal or hepatic dysfunction 20min after pneumoperitoneum percentage of patients with renal or hepatic dysfunction
- Secondary Outcome Measures
Name Time Method Change of hepatic function 20min after pneumoperitoneum the increase of hepatic ALT and AST after pneumoperitoneum
Change of renal function 20min after pneumoperitoneum Change of BUN and Cr after pneumoperitoneum
Trial Locations
- Locations (1)
Xijing Hospital, Fourth Military Medical University
🇨🇳Xi'an, Shaanxi, China
Xijing Hospital, Fourth Military Medical University🇨🇳Xi'an, Shaanxi, China