TEAS to Reduce Propofol Consumption During General Anesthesia

Not Applicable

Completed

• Conditions: Anesthesia
• Interventions: Other: electrodes attached; Other: acupoint stimulation; Other: non-acupoint stimulation

• Registration Number: NCT02314650
• Lead Sponsor: Air Force Military Medical University, China

Brief Summary

The study is aimed at whether transcutaneous electrical acupoint stimulation (TEAS) during general anesthesia could reduce the need for propofol in patients undergoing minor surgery.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-12-07
• Study First Submitted QC: 2014-12-09
• Study First Posted: 2014-12-11
• Study Start: 2015-08-25
• Primary Completion: 2017-12-28
• Study Completion: 2017-12-29
• Status Verified: 2022-11
• Last Update Submitted: 2022-11-08
• Last Update Posted: 2022-11-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 162

Inclusion Criteria

• Patients undergoing minor surgeries including laparoscopic surgery and breast surgery under general anesthesia
• Patients with written informed consent

Exclusion Criteria

• Patients with difficulty to communicate,including psychiatric disorder and Alzheimer's disease
• Patients with drug abuse
• Patients with disease of central nervous system
• Patients with renal or hepatic dysfunction

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	electrodes attached	patients were with electrodes attached but no stimulation was given
Transcutaneous acupoint stimulation	acupoint stimulation	Electrical stimulation was given through electrodes attached to skin at Ximen and Shenmen acupoint during anesthesia
Transcutaneous acupoint stimulation	electrodes attached	Electrical stimulation was given through electrodes attached to skin at Ximen and Shenmen acupoint during anesthesia
Non-acupoint stimulation	electrodes attached	Electrical stimulation was given through electrodes attached to skin at shoulder (non-acupoint) during anesthesia
Non-acupoint stimulation	non-acupoint stimulation	Electrical stimulation was given through electrodes attached to skin at shoulder (non-acupoint) during anesthesia

Primary Outcome Measures

Name	Time	Method
propofol consumption	from induction to the end of surgery,at an average of 1 hour

Secondary Outcome Measures

Name	Time	Method
effect site concentration of propofol at awake	from end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
nausea and vomiting during stay at postanesthesia care unit	30min after surgery
time to extubation	from end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
time to awake	from end of propofol infusion to open eyes to verbal command,at an average of 30 minutes
highest sedation score during stay at postanesthesia care unit	from end of surgery to discharge from post anesthesia care unit, at an average of 1 hour

Trial Locations

Locations (1)

Xijing Hospital; 🇨🇳 Xi'an, Shaanxi, China