Transcutaneous Electrical Acupoint Stimulation to Improve Pregnancy Rates for Women Undergoing in Vitro Fertilization

Not Applicable

• Conditions: Supervision of Pregnancy Resulting From In-vitro Fertilization
• Interventions: Device: transcutaneous electrical acupoint stimulation (TEAS);EA

• Registration Number: NCT01608048
• Lead Sponsor: Huazhong University of Science and Technology

Brief Summary

The objective of this study is to investigate the effect of transcutaneous electrical acupoint stimulation on pregnancy rates in women undergoing in vitro fertilization.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-05-24
• Study First Submitted QC: 2012-05-29
• Study First Posted: 2012-05-30
• Status Verified: 2012-11
• Last Update Submitted: 2014-03-29
• Last Update Posted: 2014-04-01
• Study Start: 2014-05
• Primary Completion: 2016-04
• Study Completion: 2017-02

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 384

Inclusion Criteria

(1) infertile women < 40 years of age, undergoing a fresh IVF or intracytoplasmic sperm injection (ICSI) cycle; (2) be an appropriate candidate with the potential for a lower success rate which defined as two or more previous unsuccessful ETs (fresh or frozen); (3) are willing to sign an informed consent form, indicating that they are aware of the investigational nature of this study that is in keeping with the policies of the institution; (4) willing to return to the study site for their study visits. The reason for our inclusion criteria is that women experienced several unsuccessful OAs or ETs may easily accept randomization to this study, and for whom adding TEAS or EA may significantly improve their clinical outcomes.

Exclusion Criteria

(1) major medical illnesses (like stage III heart disease, severe hypertension, uncontrolled diabetes mellitus, HIV positivity, severe bleeding dyscrasias, etc.) possibly precluding IVF or pregnancy; (2) FSH more than 20 IU/L; (3) receiving donor eggs; (4) cutaneous lesion of certain acupoint area; (5) having been previously participated in this study or having undertaken acupuncture (in whatever modality) treatment for infertility.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
TEAS	transcutaneous electrical acupoint stimulation (TEAS);EA	-
EA:electro-acupuncture	transcutaneous electrical acupoint stimulation (TEAS);EA	-

Primary Outcome Measures

Name	Time	Method
clinical pregnancy rate (CPR)	1 year

Secondary Outcome Measures

Name	Time	Method
Live birth rate (LBR)	2 years

Trial Locations

Locations (1)

IVF center of Tongji Hospital,Tongji medical college,HUST; 🇨🇳 Wuhan, Hubei, China