Transcutaneous Electrical Acupoint Stimulation Decreases Remifentanil Consumption and Postoperative Pain in Patients Undergoing Radical Mastectomy: Dual Acupoints Versus Single Acupoint in a Prospective Randomized Controlled Trial

Xijing Hospital1 site in 1 country153 target enrollmentJuly 2015

ConditionsPostoperative Acute Pain Chronic Pain

Overview

Phase: N/A
Intervention: Not specified
Conditions: Postoperative
Sponsor: Xijing Hospital
Enrollment: 153
Locations: 1
Primary Endpoint: dose of remifentanil during anesthesia
Status: Completed
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

The purpose of this study is to evaluate the effects of transcutaneous electric acupoint stimulation(TEAS) at single acupoint or dual acupoints on opioid consumption and postoperative pain in patients undergoing radical mastectomy

Registry

clinicaltrials.gov

Start Date

July 2015

End Date

June 2016

Last Updated

7 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Xijing Hospital

Responsible Party

Principal Investigator

wangqiang

Professor

Xijing Hospital

Eligibility Criteria

Inclusion Criteria

•patients aged from 18 to 65 yrs
•body mass index (BMI) of 18 to 30 kg/m2
•elective radical mastectomy under general anesthesia

Exclusion Criteria

•contradictions to electric stimulation
•difficulties in communication
•histories of general anesthesia, drug or alcohol abuse or addiction
•cardiac dysfunction or severe hypertension, confirmed hepatic dysfunction and renal impairment
•participants recruited into other clinical trials during last three months

Outcomes

Primary Outcomes

dose of remifentanil during anesthesia

Time Frame: from start of anesthesia to extubation, on average 2 hours

Secondary Outcomes

incidence of respiratory depression during recovery(from extubation to discharge from post anesthesia care unit, approximately 40 minutes on average)
visual analogue scale during recovery(from arriving to discharge from post anesthesia care unit, approximately 30 minutes on average)
pain score at 6 months after surgery(from discharge from hospital to 6 months after surgery, approximately 3 months)
time to extubation(from end of remifentanil infusion to extubation,approximately 10 minutes on average)
incidence of nausea and vomiting during recovery(from extubation to discharge from post anesthesia care unit, approximately 40 minutes on average)
time to recall(from end of remifentanil infusion to patient response to verbal command,approximately 10 minutes on average)
visual analogue scale at 24 hour after surgery(from end of surgery to 24 hours after surgery, totally 24 hours)
pain score at 3 months after surgery(from discharge from hospital to 3 months after surgery, approximately 3 months)