Identifying risk factors for dental erosion - is salivary enzyme activity abiomarker?
- Conditions
- Erosion of teethK03.2
- Registration Number
- DRKS00005191
- Lead Sponsor
- Medizinische Zentrum für Zahn-, Mund- und KieferheilkundePoliklinik für Zahnerhaltungskunde und Präventive Zahnheilkunde
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting withdrawn before recruiting started
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
age of consent; informed written consent; Groups suffering from erosion: BEWE score of at least 2 in at least two sextants
Exclusion Criteria
cavitated carious lesions; insufficient fillings reaching the dentine; deep and inflamed periodontal pockets (= 4 mm with bleeding); other serious inflammatory processes in the oral cavity; allergy against the used dental materials
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Activity of oral proteolytic enzymes (pepsin, trypsin, salivary collagenases,<br>general proteolytic activity); correlation of activity with type of acid and with<br>occurence of erosion
- Secondary Outcome Measures
Name Time Method