Smellprints in lung Cancer; the role of ENose in diagnosis and Treatment (SCENT): part 4. Diagnostic value of the eNose in Head and Neck Cancer

Completed

• Conditions: head neck cancer; oropharyngeal carcinoma; 10043946; 10038364; 10029107

• Registration Number: NL-OMON34633
• Lead Sponsor: Medisch Centrum Leeuwarden

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 40

Inclusion Criteria

Written informed consent obtained.
Head and neck cancer:
• adult 18-8o years
• head and neck cancer of oral and pharyngeal area
• Histology: squamous cell carcinoma
controls:
Matched for:
• Age: <50 yr, 50=• smoking status: two groups
A. never, or ex-smoker > 3 months
B. current smoker or ex-smoker < 3 months.
• sex

Exclusion Criteria

consumption of alcohol in last 48 hours prior to the test.
severe paradontitis
• any infection (especially of the airways) in the last 4 weeks
• Other known pulmonary disease
• Other or former malignancy
• Diabetes mellitus (documented in the past)
• Pregnancy
• Untreated hypercholesterolaemia (documented in the past)
• Significant cardiovascular disease (documented in the past)
eating (including chewing gum), drinking, smoking < 3 hours before measurements.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>primary outcome parameter is the difference in breathprints provided by the<br /><br>electronic nose </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>not applicable</p><br>