NCT00819442Unknown不适用
Relationship Between Abnormalities of Desmin Cytoskeleton, Mitochondrial Activity and Expression of Ubiquitin in Aspect of Pathogenesis of Heart Failure and Prognosis.
Ministry of Scientific Research and Information Technology, Poland2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2009年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- all cause mortality
研究概览
简要总结
The purpose of this study is evaluation of expression of desmin in cardiomyocytes of patients with idiopathic dilated cardiomyopathy. Analysis of relationship between desmin expression and activities of mitochondrium and expression of ubiquitin.
研究设计
- 研究类型
- Interventional
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •idiopatic dilated cardiomyopathy, NYHA I, II, III, IV
- •dilated left ventricle
- •ejection fraction below 45%
排除标准
- •diabetes mellitus
- •kidney failure (GFR < 30, creatinine below 2,5 mg/dl
结局指标
主要结局
all cause mortality
时间窗: one year
次要结局
- qualitative differences in desmin expression in cardiomyocytes of patient with heart failure(one year)
研究者
研究点 (2)
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