Vitamin D supplementation prior to surgery for colorectal cancer: a randomised pilot study.

Phase 2

• Conditions: Colorectal Cancer; Cancer - Bowel - Back passage (rectum) or large bowel (colon)

• Registration Number: ACTRN12610000936022
• Lead Sponsor: niversity of Otago

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-11-03
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Patients with colon cancer as diagnosed by colonoscopy, CT or Barium enema scheduled for elective surgery at Dunedin Hospital.
Participant is willing and able to give informed consent for participation in the study.
Willing to allow his or her General Practitioner and consultant, if appropriate, to be notified of participation in the study.

Exclusion Criteria

Hypercalcaemia (> 2.6mmol/L).
Hypervitaminosis D.
Renal osteodystrophy with hyperphosphatemia.
Renal failure (requiring renal replacement therapy).
Sarcoidosis and possibly other granulomatous diseases.
Patients receiving treatment with thiazide diuretics.
Advanced liver disease (Childs-Pugh B or C).
Patients in whom there would be less than 7 days between randomisation and surgery.
Female participants who are pregnant, lactating or planning pregnancy during the course of the study.
Patients with rectal cancer due to difficulties obtaining fresh tissue without compromising histopathological examination.

Study & Design

• Study Type: Interventional
• Study Design: Not specified