Atrioventricular septal defect: longterm follow-up after correctio
Recruiting
- Conditions
- atrioventricular septal defecthole in wall between atria and ventricles1001039410007510
- Registration Number
- NL-OMON37347
- Lead Sponsor
- eids Universitair Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 70
Inclusion Criteria
Living patients after AVSD correction performed at the LUMC/AMC
>8years of age
No chromosomal abnormalities
No contra-indications for exercise test: severe aortic stenosis, inability to cycle.
No contra-indications for MRI examination: PM dependency, claustrofobia
Age-matched healthy controls
Exclusion Criteria
<8years of age
Chromosomal abnormalities
Contra-indications for exercise test: severe aortic stenosis, inability to cycle.
Contra-indications for MRI examination: PM dependency, claustrofobia
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Main study parameter<br /><br>Echocardiography: peak systolic strain<br /><br>MRI: AVV-function, percentage of AVV regurgitation.<br /><br></p><br>
- Secondary Outcome Measures
Name Time Method <p>Clinical status, peak oxygen uptake. Dimensions and function of left and right<br /><br>atria en ventricles.</p><br>