Treatment of Early Nasal Polyposis With Topical Triamcinolone
- Registration Number
- NCT01222871
- Brief Summary
The purpose of this study is to compare the effectiveness of intranasal Triamcinolone delivered through a bio-absorbable nasal dressing verses oral steroids and a saline soaked dressing, in the treatment and prevention of early nasal polyposis.
- Detailed Description
nasopore, a bio-absorbable nasal dressing, may offer an alternative route of sustained steroid drug delivery. The use of topical targeted intranasal steroids may prevent the routine adverse effects of oral steroids while maintaining the same therapeutic / clinical efficacy.
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 1
Inclusion Criteria
- Age > 18 years
- Patients with early nasal polyposis
Exclusion Criteria
- Age < 18 years
- Patients with active sinus infections
- Patients on long term steroids
- Allergy or sensitivity to steroids
- Patients with Antrochoanal polyps
- Patients who received topical steroids by bio-resorbable sponge or oral steroids
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Control Group Saline soaked sponge Saline soaked sponge Triamcinolone Triamcinolone Triamcinolone soaked nasopore dressing
- Primary Outcome Measures
Name Time Method Nasal Endoscopic Exam Findings . 2 weeks, 6 weeks, 12 weeks were not collected from any participant. nasal endoscopic exam findings at 2 weeks, 6 weeks and 12 weeks were not collected from any participant.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
St. Elizabeth's Medical Center, 736 Cambridge St
🇺🇸Brighton, Massachusetts, United States