Overview
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate. Triamcinolone was granted FDA approval on 3 December 1957. In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval - for the treatment of patients with macular edema associated with uveitis.
Background
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, or first line as a topical treatment of corticosteroid responsive dermatoses. Triamcinolone is more commonly seen in the forms triamcinolone hexacetonide, triamcinolone acetonide, and triamcinolone diacetate. Triamcinolone was granted FDA approval on 3 December 1957. In October 2021, a suspension of triamcinolone acetonide was approved for suprachoroidal injection - the first suprachoroidal injection to receive FDA approval - for the treatment of patients with macular edema associated with uveitis.
Indication
肾上腺皮质激素类药。主要用于过敏性与自身免疫性炎症性疾病。由于本品潴钠作用较弱，故一般不用作肾上腺皮质功能减退的替代治疗。
Associated Conditions
- Acne
- Acne Vulgaris
- Acute Gouty Arthritis
- Allergic Contact Dermatitis
- Allergic Rhinitis (AR)
- Allergic Skin Reaction
- Alopecia Areata (AA)
- Ankylosing Spondylitis (AS)
- Aphthous Stomatitis
- Asthma
- Atopic Dermatitis
- Autoimmune Hemolytic Anemia
- Berylliosis
- Bullous dermatitis herpetiformis
- Chronic Eczema
- Chronic Inflammatory Skin Diseases
- Congenital Adrenal Hyperplasia (CAH)
- Congenital Hypoplastic Anemia
- Contact Dermatitis
- Crohn's Disease (CD)
- Dental Cavity
- Dermatitis
- Dermatomyositis (DM)
- Diaper Rash
- Discoid Lupus Erythematosus (DLE)
- Edema of the cerebrum
- Epicondylitis
- Erythroderma
- Fungal Infections
- Fungal infectious disorders of the Beard
- Fungal skin infection
- Gingivitis
- Haemorrhoids
- Hemangiomas
- Hypercalcemia
- Inflammation of Mouth
- Intertrigo
- Itching of the Anus
- Itching of the External Genitalia
- Itching of the Foot
- Itching of the genitals
- Itching of the hand
- Juvenile Idiopathic Arthritis (JIA)
- Keloids Scars
- Leukemias
- Lichen Planus (LP)
- Lichen simplex chronicus
- Lymphoma
- Macular Edema
- Mycosis Fungoides (MF)
- Mycotic Eczema
- Necrobiosis lipoidica diabeticorum
- Neurodermatitis
- Nummular Dermatitis
- Ocular Inflammation
- Ophthalmia, Sympathetic
- Oral Erosive Lichen Planus
- Otitis Externa
- Pemphigus
- Pericarditis
- Polymyositis
- Postherpetic Neuralgia
- Primary adrenocortical insufficiency
- Proteinuria
- Psoriasis Vulgaris (Plaque Psoriasis)
- Psoriatic Arthritis
- Psoriatic plaque
- Pure Red Cell Aplasia
- Purulent Wounds
- Pyoderma caused by susceptible bacteria
- Regional Enteritis
- Rheumatoid Arthritis
- Ringworm Folliculitis
- Seborrheic Dermatitis
- Seborrheic Dermatitis, Eczematous
- Secondary Impetiginization
- Secondary adrenocortical insufficiency
- Secondary thrombocytopenia
- Serum Sickness
- Skin chapped
- Stomatitis, Denture
- Synovitis
- Systemic Lupus Erythematosus
- Temporal Arteritis
- Tinea Corporis
- Transfusion Reactions
- Trichinosis
- Tuberculosis (TB)
- Ulcerative Colitis
- Urticaria
- Uveitis
- Wound Infections
- Acute Bursitis
- Acute Multiple sclerosis
- Acute Rheumatic heart disease, unspecified
- Acute Tenosynovitis
- Corticosteroid-responsive dermatoses
- Cutaneous candidiasis
- Cystic tumour of the ganglia
- Exfoliative erythroderma
- Granuloma annulare lesions
- Idiopathic eosinophilic pneumonias
- Non-suppurative Thyroiditis
- Oral infections
- Oral lesions
- Severe Erythema multiforme
- Subacute Dermatitis, Eczematous
- Symptomatic Sarcoidosis
- Ulceration of the mouth
- Ulcerative stomatitis
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2025/06/24 | N/A | Completed | Maharajgunj Medical Campus | ||
2025/06/10 | Phase 4 | Active, not recruiting | Kasr El Aini Hospital | ||
2025/06/05 | Phase 4 | Recruiting | |||
2025/05/29 | Phase 2 | Active, not recruiting | |||
2025/05/18 | Phase 2 | Not yet recruiting | |||
2025/04/20 | Phase 4 | Not yet recruiting | |||
2025/03/27 | Phase 4 | Not yet recruiting | Nishtar Medical University | ||
2025/02/07 | Phase 2 | Active, not recruiting | |||
2025/02/06 | Phase 1 | ENROLLING_BY_INVITATION | |||
2025/01/29 | Not Applicable | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Macleods Pharmaceuticals Limited | 33342-329 | TOPICAL | 1 mg in 1 g | 7/1/2023 | |
| NuCare Pharmaceuticals,Inc. | 68071-2491 | TOPICAL | 1 mg in 1 g | 8/4/2021 | |
| MICRO LABS LIMITED | 42571-385 | TOPICAL | 1 mg in 1 mL | 8/10/2021 | |
| Alembic Pharmaceuticals Inc. | 62332-606 | TOPICAL | 1 mg in 1 g | 12/12/2023 | |
| Crown Laboratories | 0316-0175 | TOPICAL | 5 mg in 1 g | 10/24/2023 | |
| Bryant Ranch Prepack | 63629-2495 | TOPICAL | 1 mg in 1 g | 2/15/2022 | |
| Sincerus Florida, LLC | 72934-2166 | TOPICAL | 0.1 g in 100 g | 5/13/2019 | |
| NorthStar Rx LLC | 16714-150 | INTRA-ARTICULAR, INTRAMUSCULAR | 400 mg in 10 mL | 1/23/2024 | |
| Physicians Total Care, Inc. | 54868-6270 | NASAL | 55 ug in 1 1 | 9/27/2011 | |
| Bryant Ranch Prepack | 63629-2407 | TOPICAL | 0.147 mg in 1 g | 2/23/2021 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| ECOCORT CREAM | SIN10246P | CREAM | 0.1%w/w | 10/9/1998 | |
| ORREPASTE 0.1% w/w | SIN11484P | PASTE | 0.1% w/w | 4/9/2001 | |
| ORACORT E DENTAL PASTE | SIN04682P | PASTE | 0.1% w/w | 6/13/1990 | |
| SHINCORT I.M. INJECTION 40 mg/ml | SIN05787P | INJECTION | 40 mg/ml | 4/26/1991 | |
| ORAMEDY PASTE 1 mg/g | SIN04004P | PASTE | 1 mg/g | 3/20/1990 | |
| SHINCORT INJECTION 10 mg/ml | SIN06709P | INJECTION | 10 mg/ml | 12/3/1991 | |
| KENO ORAL PASTE 1 mg/g | SIN11853P | PASTE | 1 mg/g | 3/21/2002 | |
| TRIAMCINOLONE ACETONIDE 40 mg/ml | SIN06648P | INJECTION | 40 mg/ml | 10/24/1991 | |
| NASACORT AQ NASAL SPRAY 55 mcg/actuation | SIN10821P | SPRAY | 55 mcg/actuation | 3/19/1999 | |
| ECONAZINE CREAM | SIN06601P | CREAM | 1 mg/g | 10/1/1991 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| Triamcinolone Tablets | 国药准字H10960056 | 化学药品 | 片剂 | 7/28/2020 | |
| Triamcinolone Acetonide Acetate And Chloramphenicol Solution | 国药准字H13024373 | 化学药品 | 溶液剂 | 9/29/2020 | |
| Triamcinolone Acetonide Acetate Nasal Spray | 国药准字H20030910 | 化学药品 | 喷雾剂 | 12/7/2020 | |
| Triamcinolone Acetonide Dental Paste | 国药准字HC20181015 | 化学药品 | 软膏剂 | 3/16/2023 | |
| Triamcinolone Acetonide Acetate Injection | 国药准字H33020762 | 化学药品 | 注射剂 | 4/26/2020 | |
| Triamcinolone Acetonide Acetate Injection | 国药准字H33020825 | 化学药品 | 注射剂 | 4/26/2020 | |
| Triamcinolone Acetonide Acetate Injection | 国药准字H12020607 | 化学药品 | 注射剂 | 7/27/2020 | |
| Triamcinolone Acetonide Acetate Injection | 国药准字H12020606 | 化学药品 | 注射剂 | 7/27/2020 | |
| Triamcinolone Acetonide Acetate Injection | 国药准字H20033524 | 化学药品 | 注射剂 | 4/26/2020 | |
| Triamcinolone Acetonide Acetate Injection | 国药准字H33021092 | 化学药品 | 注射剂 | 4/26/2020 |
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| TRIAMCINOLONE CREAM 0.2% (VIDA) | N/A | N/A | N/A | 5/19/1979 | |
| LONGAXON CREAM | N/A | N/A | N/A | 1/14/1997 | |
| PROMAX CREAM | N/A | N/A | N/A | 12/29/2004 | |
| MUCOCARE GEL | N/A | N/A | N/A | 11/19/2007 | |
| ECONAZINE CREAM | N/A | N/A | N/A | 10/17/1990 | |
| FLUODERMA CREAM | N/A | N/A | N/A | 2/1/1996 | |
| TRISONIN AQUEOUS NASAL SPRAY 55MCG/DOSE | N/A | N/A | N/A | 9/26/2022 | |
| ROMACOMB CREAM | N/A | N/A | N/A | 5/22/1992 | |
| QUESITAN CREAM | N/A | N/A | N/A | 10/10/1995 | |
| ORIBIOTIC OINT (VET) | N/A | N/A | N/A | 8/12/1999 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| TRICORTONE 0.02% OINTMENT triamcinolone acetonide 0.2mg/g tube | 95812 | Medicine | A | 7/30/2003 | |
| TRICORTONE 0.02% CREAM triamcinolone acetonide 0.2mg/g tube | 95811 | Medicine | A | 7/30/2003 | |
| ARISTOCORT 0.02% OINTMENT triamcinolone acetonide 0.2mg/g tube | 15123 | Medicine | A | 9/9/1991 | |
| Kenacomb Otic Ointment tube | 19201 | Medicine | A | 9/30/1991 | |
| ARISTOCORT 0.02% CREAM triamcinolone acetonide 0.2mg/g tube | 15121 | Medicine | A | 9/9/1991 | |
| Kenacort-A 10 10mg/1mL injection ampoule | 19204 | Medicine | A | 9/30/1991 | |
| OTOCOMB Otic ear drops bottle | 56477 | Medicine | A | 8/7/1996 | |
| KENACORT-A 40 triamcinolone acetonide 40mg/mL injection ampoule | 49226 | Medicine | A | 9/29/1995 | |
| Kenacomb Otic ear drops bottle | 19200 | Medicine | A | 9/30/1991 | |
| Kenacomb Ointment tube | 19197 | Medicine | A | 9/30/1991 |