Suprachoroidal Triamcinolone in Macular Edema for Patients With Non-Infectious Uveitis Resistant to Subtenon Triamcinolon
试验速览
- 阶段
- 1 期
- 状态
- 招募中
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Visual acuity improvement
研究概览
简要总结
The goal of this study is to learn if a suprachoroidal triamcinolone injection can treat vision-threatening swelling in the center of the retina (macular edema) caused by non-infectious uveitis, especially in people who did not improve after a standard steroid injection around the eye (sub-Tenon injection).
The main questions it aims to answer are:
Does vision improve on the eye chart after the injection?
Does the injection lower retinal swelling (reduction in thickness) within 3 months?
Participants will:
Have a pre-treatment check (vision test, slit-lamp exam, and a retinal scan called OCT).
Receive one suprachoroidal triamcinolone injection under anesthetics drops in a sterile setting (operating room) with standard monitoring.
Return for visits about 1 month and 3 months after treatment for repeat vision tests, and OCT scans.
Contact the clinic if they notice pain, redness, new floaters, or worsening vision.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non-infectious uveitis complicated with macular edema
- •Uveitic macular edema of less than four months' duration
- •Macular edema persisted despite lack of intra-ocular inflammation
- •No response to posterior sub-Tenon triamcinolone acetonide injections
排除标准
- •Those with epiretinal membrane-associated macular edema
- •Below 18 years
研究组 & 干预措施
Suprachoroidal Triamcinolone treatment arm
干预措施: Suprachoroidal triamcinolone acetonide injection (Drug)
结局指标
主要结局
Visual acuity improvement
时间窗: 3 months
visual acuity improvement was defined as a gain of two or more lines in visual acuity or a reduction in logMAR values
次要结局
- Central Macular Thickness(3 Months)
研究者
Mohammed Mutar
Medical Doctor
Baghdad college of medicine