Intravitreal Triamcinolone for Acute Branch Retinal Vein Occlusion
- Conditions
- Branch Retinal Vein Occlusion
- Registration Number
- NCT00370266
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
The purpose of this study is to determine whether intraocular injection of triamcinolone is effective in the treatment of macular edema in acute branch retinal vein occlusion.
- Detailed Description
Intravitreal triamcinolone has recently been shown to have beneficial effect on chronic macular edema due to vein occlusion and preventive effect on neovascularization. Hypothetically, prevention of macular derangement by reducing the amount of edema from early phase after occlusion until restoration of collaterals seems to be helpful in these eyes. To our knowledge, no prospective randomized clinical trial, considering both macular changes and preventive effect on neovascularization has been published for intravitreal triamcinolone in acute branch retinal vein occlusion.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- Eyes suffering from branch retinal vein occlusion with less than 2 months duration.
- Monocularity,
- Previous intraocular surgery or laser therapy
- Glaucoma or ocular hypertension
- Significant media opacity
- Existence of traction on the macula
- Visual acuity ≥20/40
- Signs of chronicity (such as cilioretinal and/or retinal shunt vessels)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Central macular thickness
- Secondary Outcome Measures
Name Time Method Visual acuity Retinal neovascularization Intraocular pressure Cataract progression
Trial Locations
- Locations (1)
Alireza Ramezani, MD
🇮🇷Tehran, Iran, Islamic Republic of