Use of Intravitreal Triamcinolone and Retrobulbar Chlorpromazine as Alternatives to the Management of Painful Blind Eye
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Changes in Pain intensity
研究概览
简要总结
The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of ocular pain in blind eyes.
详细描述
The management of chronic eye pain is a constant challenge to ophthalmology. Treatment varies with the intensity of pain, and topical eye drops and contact lens therapy are effective in many patients. In refractory cases, and without vision, surgical removal of the eye through enucleation is considered classical therapy. As less invasive alternatives we have cyclodestruction and neurolytic drug injection in order to promote analgesia for a prolonged period.
The purpose of this study is to evaluate the efficacy of intravitreal triamcinolone and retrobulbar chlorpromazine as alternatives in the management of This is a prospective study of patients with blind painful eyes not responsive to topical treatment and with no indication for evisceration seen at the Department of Ophthalmology, Hospital Governador Celso Ramos (HGCR) in 2010.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients treated in the period at HGCR who wanted to be part of the protocol by signing the consent form
排除标准
- •patients whose follow-up period was less than three months
研究组 & 干预措施
Intravitreal Triamcinolone
Patients with phthisis bulbi received 0,3ml intravitreal triamcinolone injection
干预措施: Triamcinolone (Drug)
Retrobulbar Chlorpromazine
Patients with refractory glaucoma and blind painful eye were submitted to 2,5mL Chlorpromazine retrobulbar injection
干预措施: Chlorpromazine (Drug)
结局指标
主要结局
Changes in Pain intensity
时间窗: 0, 1 month, 3 months, 6 months after procedure
Pain was measured asking the patient to graduate it in a scale from 0 to 10, 0 being no pain, 10 being the worst pain patient has experienced in life
次要结局
- Changes in Use of eyedrops before and after drug injection(0, 1 month, 3 months, 6 months)
- Changes in Intraocular pressure (IOP)(0, 1 months, 3 months, 6 months)