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Clinical Trials/NCT05496530
NCT05496530
Unknown
Not Applicable

One Year Results for Suprachoroidal Triamcinolone Acetonide Injection in Various Retinal Diseases

Benha University1 site in 1 country100 target enrollmentJuly 10, 2022

Overview

Phase
Not Applicable
Intervention
Suprachoroidal triamcinolone acetonide injection
Conditions
Diabetic Macular Edema
Sponsor
Benha University
Enrollment
100
Locations
1
Primary Endpoint
Visual acuity
Last Updated
3 years ago

Overview

Brief Summary

Suprachoroidal drug delivery is a recent route for managing various ocular conditions. Safety and long term results are still under investigations.

Detailed Description

In this study, we aim to analyze the long term results of suprachoroidal injection in treating various retinal diseases to focus on its efficacy, safety and long term ocular effects as ocular hypertension, cataract progression and macular edema resolution.

Registry
clinicaltrials.gov
Start Date
July 10, 2022
End Date
August 15, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ahmed Abdelshafy

Lecturer of Ophthalmology

Benha University

Eligibility Criteria

Inclusion Criteria

  • cases with central macular thickness more than 250 microns measured by optical coherence tomography due to one of the following conditions:
  • Diabetic macular edema
  • Vogt-koyanagi Harada disease
  • Retinal vein occlusion.

Exclusion Criteria

  • other causes of increased macular thickness as age related macular degeneration and myopic choroidal new vascularization.
  • Cases with confirmed diagnosis of glaucoma.

Arms & Interventions

Diabetic macular edema

Cases with diabetic macular edema with central macular thickness more than 300 microns measured by optical coherence tomography.

Intervention: Suprachoroidal triamcinolone acetonide injection

Vogt-koyanagi harada

Cases with vogt-koyanagi harada and complicated with exudative retinal detachment confirmed by optical coherence tomography.

Intervention: Suprachoroidal triamcinolone acetonide injection

Retinal vein occlusion

Cases with retinal vein occlusion and complicated with macular edema confirmed by optical coherence tomography.

Intervention: Suprachoroidal triamcinolone acetonide injection

Outcomes

Primary Outcomes

Visual acuity

Time Frame: Baseline and up to one year after injection.

Changes noted in vision after injection measured 8n logMar units by snellen chart.

Secondary Outcomes

  • Central macular thickness(Baseline and up to one year after injection.)

Study Sites (1)

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