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Clinical Trials/NCT05337332
NCT05337332
Unknown
Phase 2

Suprachoroidal Triamcinolone Acetonide Injection in Two Chorioretinal Diseases: One Year Results

Benha University1 site in 1 country50 target enrollmentApril 14, 2022

Overview

Phase
Phase 2
Intervention
Triamcinolone Acetonide
Conditions
Central Serous Chorioretinopathy
Sponsor
Benha University
Enrollment
50
Locations
1
Primary Endpoint
Central macular thickness
Last Updated
4 years ago

Overview

Brief Summary

Suprachoroidal injection is a safe way for intraocular drug delivery. It was used to treat various retinal conditions.

Detailed Description

Suprachoroidal triamcinolone acetonide injection is used to treat various retinal diseases, higher concentration of the injected material is found when the suprachoroidal space is used as an intraocular delivery pathway when compared to the conventional intravitreal pathway.

Registry
clinicaltrials.gov
Start Date
April 14, 2022
End Date
June 1, 2023
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ahmed Abdelshafy

Assistant professor of Ophthalmology

Benha University

Eligibility Criteria

Inclusion Criteria

  • patients diagnosed as central serous chorioretinopathy and patients with cystoid macular edema due to irvine-gass syndrome after cataract surgery.

Exclusion Criteria

  • other retinal diseases that may affect CMT and final visual outcome.
  • Patients with dense corneal opacity.

Arms & Interventions

Central serous chorioretinopathy group

Cases with central serous chorioretinopathy (CSR) that will be injected with suprachoroidal triamcinolone acetonide.

Intervention: Triamcinolone Acetonide

Irvine-Gass Syndrome group

Cases with cystoid macular edema due to irvine-gass syndrome that will be injected with suprachoroidal triamcinolone acetonide

Intervention: Triamcinolone Acetonide

Outcomes

Primary Outcomes

Central macular thickness

Time Frame: Baseline and 12 months after injection.

Changes in central macular thickness (CMT) measured in millimeters (mm) by optical coherence tomography (OCT)

Secondary Outcomes

  • Best corrected visual acuity(Baseline and 12 months after injection.)

Study Sites (1)

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