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CLEARSIDE BIOMEDICAL INC

🇺🇸United States

Country: 🇺🇸United States

Ownership: Public

Established: 2011-01-01

Employees: 30

Market Cap: $75.4M

Website: http://www.clearsidebio.com

Clinical Trials

Study to Evaluate Suprachoroidally Administered CLS-AX in the Treatment of Neovascular Age-Related Macular Degeneration

Phase 2

Completed

Conditions: Neovascular Age-related Macular Degeneration

Interventions: Drug: CLS-AX
Drug: Aflibercept

First Posted Date: 2023-06-07

Last Posted Date: 2025-01-09

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 60

Registration Number: NCT05891548

Locations: 🇺🇸
Associated Retina Consultants, Phoenix, Arizona, United States
🇺🇸
Retinal Research Institute, LLC, Phoenix, Arizona, United States
🇺🇸
California Retina Consultants, Bakersfield, California, United States

and more 29 locations

Extension Study to Evaluate the Long-term Outcomes of Subjects in the CLS-AX CLS1002-101 Study

Completed

Conditions: Neovascular Age-related Macular Degeneration

Interventions: Drug: CLS-AX

First Posted Date: 2021-11-23

Last Posted Date: 2024-03-04

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 15

Registration Number: NCT05131646

Locations: 🇺🇸
Retinal Consultants of Arizona, Phoenix, Arizona, United States
🇺🇸
Northern California Retina Vitreous Associates Medical Group, LLC, Mountain View, California, United States
🇺🇸
Retina Consultants Medical Group, Inc, Sacramento, California, United States

and more 3 locations

Safety and Tolerability Study of Suprachoroidal Injection of CLS-AX Following Anti-VEGF Therapy in Neovascular AMD

Phase 1

Completed

Conditions: Neovascular Age-related Macular Degeneration

Interventions: Drug: CLS-AX
Drug: Anti-VEGF

First Posted Date: 2020-11-12

Last Posted Date: 2023-09-18

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 27

Registration Number: NCT04626128

Locations: 🇺🇸
Retinal Consultants of Arizona, Phoenix, Arizona, United States
🇺🇸
California Retina Consultants, Bakersfield, California, United States
🇺🇸
Northern California Retina Vitreous Associates Medical Group, LLC, Mountain View, California, United States

and more 6 locations

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO

Phase 3

Terminated

Conditions: Retinal Vein Occlusion
Macular Edema

Interventions: Drug: suprachoroidal CLS-TA
Drug: suprachoroidal sham
Drug: Lucentis or Avastin

First Posted Date: 2017-06-29

Last Posted Date: 2021-04-23

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 325

Registration Number: NCT03203447

Locations: 🇺🇸
Retinal Research Institute, Phoenix, Arizona, United States
🇺🇸
Retina Centers PC, Tucson, Arizona, United States
🇺🇸
Retina Associates Southwest PC, Tucson, Arizona, United States

and more 83 locations

Suprachoroidal CLS-TA With Intravitreal Aflibercept Versus Aflibercept Alone in Subject With Diabetic Macular Edema

Phase 2

Completed

Conditions: Diabetic Macular Edema

Interventions: Drug: IVT aflibercept
Drug: Sham SC
Drug: SC CLS-TA

First Posted Date: 2017-04-24

Last Posted Date: 2021-05-13

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 71

Registration Number: NCT03126786

Locations: 🇺🇸
Retinal Consultants of Arizona and Retinal Research Institute, Phoenix, Arizona, United States
🇺🇸
Retina Centers, PC, Tucson, Arizona, United States
🇺🇸
California Retina Consultants, Bakersfield, California, United States

and more 26 locations

Suprachoroidal Injection of CLS-TA in Patients With Non-infectious Uveitis

Phase 3

Completed

Conditions: Uveitis, Posterior
Uveitis, Anterior
Uveitis
Uveitis, Intermediate
Panuveitis

Interventions: Drug: 4 mg CLS-TA Suprachoriodal Injection

First Posted Date: 2017-03-31

Last Posted Date: 2021-06-23

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 38

Registration Number: NCT03097315

Locations: 🇺🇸
Retinal Consultants of Arizona, Phoenix, Arizona, United States
🇺🇸
Retina-Vitreous Associates Medical Group, Beverly Hills, California, United States
🇺🇸
Northern California Retina Vitreous Associates Medical Group, Inc., Mountain View, California, United States

and more 7 locations

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO

Phase 3

Terminated

Conditions: Macular Edema
Retinal Vein Occlusion

Interventions: Drug: suprachoroidal CLS-TA
Drug: suprachoroidal sham
Drug: IVT aflibercept

First Posted Date: 2016-12-02

Last Posted Date: 2021-04-14

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 460

Registration Number: NCT02980874

Locations: 🇺🇸
Associated Retina Consultants, Ltd., Phoenix, Arizona, United States
🇺🇸
Retinal Consultants of Arizona and Retinal Research Institute, Phoenix, Arizona, United States
🇺🇸
Arizona Retina and Vitreous Consultants, Phoenix, Arizona, United States

and more 105 locations

Retrospective Study of the Safety and Efficacy of Patients With RVO in Subjects Who Completed Parent Study CLS1003-201

Completed

Conditions: Macular Edema
Retinal Vein Occlusion

First Posted Date: 2016-11-06

Last Posted Date: 2019-12-20

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 20

Registration Number: NCT02956330

MAGNOLIA: Extension Study of Patients With Non-infectious Uveitis Who Participated in CLS1001-301

Completed

Conditions: Uveitis
Uveitis, Intermediate
Panuveitis
Uveitis, Anterior
Uveitis, Posterior

Interventions: Drug: Sham procedure
Drug: 4 mg CLS-TA Suprachoriodal Injection

First Posted Date: 2016-11-01

Last Posted Date: 2021-06-02

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 33

Registration Number: NCT02952001

Locations: 🇺🇸
Retinal Consultants of Arizona, Phoenix, Arizona, United States
🇺🇸
Northern California Retina Vitreous Associates Medical Group, Inc., Mountain View, California, United States
🇺🇸
Retina Group of Florida, Fort Lauderdale, Florida, United States

and more 13 locations

Suprachoroidal Injection of CLS-TA Alone or With Aflibercept in Subjects With Diabetic Macular Edema

Phase 1

Completed

Conditions: Diabetic Macular Edema

Interventions: Drug: IVT Aflibercept
Drug: SC CLS-TA

First Posted Date: 2016-10-31

Last Posted Date: 2021-05-13

Lead Sponsor: Clearside Biomedical, Inc.

Target Recruit Count: 20

Registration Number: NCT02949024

Locations: 🇺🇸
Retina Vitreous Associates Medical Group Inc, Mountain View, California, United States
🇺🇸
Retina Consultants of Houston, PA, The Woodlands, Texas, United States

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