ACTRN12618002021257已完成未知
A single centre, 12-week, single arm trial to examine compliance, safety and efficacy of daily L-carnitine supplementation (1000mg) for the treatment of childhood Neurofibromatosis Type 1 (NF1)- associated muscle weakness and fatigue.
The Children's Hospital at Westmead0 个研究点目标入组 6 人开始时间: 2018年12月17日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 6
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 8 Years 至 12 Years（—）
- 性别
- All
入选标准
- •Children aged between 8-12 years old
- •Children with a confirmed clinical diagnosis of NF1 through fulfilling at least two of the NIH diagnostic criteria for NF1 and/or genetic testing
- •Children with a medical history of muscle weakness and/or fatigue
- •Children that are naïve to nutraceutical supplements, including L-carnitine, and dietary modifications.
排除标准
- •Children with cognitive impairment, an intellectual disability, or a mental illness
- •Children with insufficient knowledge of the English language to complete the required questionnaires during the study
- •Children who suffer from seizures
- •Children with NF1 skeletal abnormalities (e.g. tibial bowing or pseudarthrosis), acute foot or lower limb injuries (e.g. fracture or ankle sprain)
- •Children who are unable to comply with the research protocol (e.g. prolonged absence)
研究者
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