The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Postprandial glycemic response
研究概览
简要总结
The main objective of the current study is to investigate whether consumption of soluble fibers (isomaltodextrin [IMD], partially digestible maltodextrin) and RS4 starch will lower postprandial glycemia as well as postprandial insulin in human subjects with relatively high fasting blood glucose, when consumed with a specific amount of digestible carbohydrate (rice porridge). The primary outcome of the study is the effect of fibers on postprandial blood glucose, whereas the secondary outcome will be its effect on postprandial blood insulin.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 22 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Body mass index (18.5 kg/m² ≤ BMI ≤ 29.9 kg/m²)
- •No history of abnormal glucose metabolism
- •No ongoing use of drugs affecting blood glucose levels
- •Fasting blood glucose between 90-110 mg/dL
- •Low dietary fiber intake (less than 15 g per day)
排除标准
- •Diabetic individuals
- •Individuals with history of gastrointestinal disease
- •Pregnant or nursing women
结局指标
主要结局
Postprandial glycemic response
时间窗: Acute study: [3 hours of measurement after consumption of test food]
Blood glucose will be measured, (AUC)
次要结局
- Postprandial insulin response(Acute study: [3 hours of measurement after consumption of test food])
研究者
Bruce R. Hamaker
Distinguished Professor of Food Science
Purdue University