Does Perioperative Parenteral Nutrition Affect Outcome in Patients Undergoing Major Abdominal Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- studying the effects of TPN on mortality
研究概览
简要总结
Preoperative optimization of patients is a well known concept. Not all patients can tolerate feeds and as such TPN is given. TPN given preoperatively and continued postoperatively in selected group of patients can significantly improve the surgical outcomes and lower the morbidity as well as mortality. So the investigators aim to find the impact of TPN in malnutritional surgical patients.
详细描述
Any patient who is at risk of malnutrition as well as already malnutritioned were given preoperative TPN for 5 days. After 5 days, elective surgery was done and TPN was continued postoperatively until patient could consume 50% of their daily requirements orally. Patients who underwent emergency surgeries were also enrolled in this study as these patients could receive TPN only postoperatively.
Daily patient charting with Clavien Dindo Classification, length of stay and mortality were mentioned and verified by the operating surgical team.
Data was maintained electronically by the surgical team. Data was also entered in MS-EXCEL at the time of patient discharge. Since data was maintained on everyday basis till patient discharge and does not include follow-ups, there are no missing data.
Upon completion of study, all data will be exported to SPSS and analyzed accordingly using means, SDs, Chi-square and Fisher exact test.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients who underwent major gastrointestinal surgery and received perioperative TPN or postoperative TPN
排除标准
- •Perioperative TPN administration that did not follow the study protocol
- •TPN given for reasons other than malnutrition
结局指标
主要结局
studying the effects of TPN on mortality
时间窗: through study completion, an average of 5years
comparison of perioperative and postoperative TPN in terms of number of mortality cases
studying the effects of TPN on length of hospital stay
时间窗: through study completion, an average of 5years
comparison of perioperative and postoperative TPN in terms of mean length of stay in days
studying the effect of albumin levels on length of hospital stay
时间窗: through study completion, an average of 5years
comparison of low and normal albumin levels in terms of mean length of stay in days
studying the effect of albumin levels on mortality
时间窗: through study completion, an average of 5years
comparison of low and normal albumin levels in terms of number of mortality cases
studying the effect of albumin levels on complication using grades
时间窗: through study completion, an average of 5years
comparison of low and normal albumin levels in terms of Clavien-Dindo Classification grades
studying the effects of TPN on complications using grades
时间窗: through study completion, an average of 5years
comparison of perioperative and postoperative TPN in terms of Clavien-Dindo classification grades
次要结局
未报告次要终点
研究者
Nabin Pokharel
Prof Dr. Nabin Pokharel, Head of Department of Surgical Gastroenterology
Nepal Medical College and Teaching Hospital