Efficacy of dTMS in alcohol dependence
- Conditions
- Health Condition 1: F102- Alcohol dependenceHealth Condition 2: F102- Alcohol dependence
- Registration Number
- CTRI/2023/04/051305
- Lead Sponsor
- Central Institute of Psychiatry
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1. Patients diagnosed with mental and behavioural disorders due to use of alcohol, dependence syndrome, currently using the substance (F10.24) as per International Classification of disease 10th (ICD-10, DCR)Diagnostic criteria for research.
2. Male gender
3. Age between 18-50 years
4. Ready to give written informed consent
5. Clinical institute withdrawal assessment for alcohol revised (CIWA-ar) score less than 10.
1. Any other co-morbid substance dependence except nicotine and caffeine.
2. Participants with any co-morbid psychiatric disorder.
3. History of severe withdrawal e.g., convulsions or delirium tremens during abstinence.
4. Color-blind patients
5. Not willing to give written informed consent.
6. Patient with presence of pacemaker or other electronic implants, metal or magnetic objects in the brain.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in scores of craving as rated by Alcohol Craving Questionnaire (ACQ) and Obsessive Compulsive Drinking Scale (OCDS).Timepoint: Reduction in scores of craving as rated by Alcohol Craving Questionnaire (ACQ) and Obsessive Compulsive Drinking Scale (OCDS) as assessed at the <br/ ><br>end of 2 weeks <br/ ><br>of dTMS treatment and after 4 weeks.
- Secondary Outcome Measures
Name Time Method Changes in the amplitude and latency of the P300 component of ERP on Stroop task.Timepoint: Changes in the amplitude and latency of the P300 component of ERP on Stroop task will be assessed before and at end of 2 weeks of dTMS treatment