Effect of cryotherapy and oral antihistamine in treatment of Alopesia Areata
Phase 3
- Conditions
- Alopecia Areata.Alopecia areata
- Registration Number
- IRCT20210404050843N1
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 48
Inclusion Criteria
patient age above 12 years
Do not take another tratment for alopecia areata for at least one month before enrollment in this trial
Maximum of three hair loss patches in the scalp or beard area, each of which is a maximum of 3 by 3 cm.
No nail involvement related to alopecia areata
Exclusion Criteria
Renal or liver dysfunction
Patients with a history of allergy to antihistamines
Pregnancy or Lactation
Lack of patient cooperation to complete the treatment process
Cold intolerance
Cryoglobulinemia
History of cold urticaria
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Terminal hair regrowth percent. Timepoint: Before the intervention (at the beginning of the study )and three months after the last treatment session. Method of measurement: The evaluation is performed by the physician with the help of a questionnaire and based on the following scale:: Good response (more than 75% of terminal hair regrowth). Moderate response (between 50 and 75% of terminal hair regrowth). Poor response (between 25 to 50% of terminal hair regrowth) No response (less than 25% of terminal hair regrowth).
- Secondary Outcome Measures
Name Time Method Patient satisfaction. Timepoint: Before the intervention (at the beginning of the study) and three months after the last treatment session. Method of measurement: Patient satisfaction rate by the questionnaire based on numerical selection from one to ten (0= no effect, 1,2= minor effect, 3,4= moderate effect, 5,6= good effect, 9,10= very good effect).