Use of Topical Olive Oil Cream for Prophylaxis Against Acute Radiodermatitis in Breast Cancer Patients
- Conditions
- RadiodermatitisAcute
- Registration Number
- NCT05285943
- Lead Sponsor
- Cairo University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 132
Inclusion Criteria:<br><br> - Histological confirmation of breast malignancy,<br><br> - Surgical intervention for carcinoma of the breast with or without lymph node<br> metastasis.<br><br> - Treatment with planned course of radiation therapy 5 days a week for 3-6 weeks.<br><br> - Good Eastern Cooperative Oncology Group (ECOG) performance status (0 or 1).<br><br> - Total radiation dose of =42 Gy.<br><br>Exclusion Criteria:<br><br> - Pregnant and lactating mothers.<br><br> - Previous radiation to the chest or breast area.<br><br> - Concomitant chemotherapy.<br><br> - Concomitant medication that may cause skin reactions.<br><br> - Use of any other product on the skin at the treatment site at any time of the study.<br><br> - Active dermatitis, history of autoimmune and connective tissue diseases, skin<br> inflammatory diseases or any other specific skin disease.<br><br> - Treatment with local or oral corticosteroid, or antioxidant medications.<br><br> - Allergy to olive oil.<br><br> - Inflammatory carcinoma of the breast as well as those with a known allergy to olive<br> oil.
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Acute Radiation Dermatitis (ARD) grading
- Secondary Outcome Measures
Name Time Method Quality of Life questionnaire;Patient Satisfaction