Predictive Value of Systemic Immune Inflammation Index in the prognosis of moderate to severe Traumatic Brain Injury patients: A prospective observational study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 142
- 试验地点
- 1
- 主要终点
- To assess the predictive value of SII index for prognosis in Traumatic brain injury taking GOSE score of 5-8 as favourable prognosis.
研究概览
简要总结
This prospective observational study, will be conducted at the department of neuroanesthesia at AIIMS Rishikesh, aims to assess the predictive value of the SII index in Traumatic Brain Injury, with a particular focus on patients who have a positive prognosis, which is defined as a GOSE score of 5-8. The parameters examined consist of the values of Systemic Inflammatory Index (SII) and Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), and Lymphocyte-to-Monocyte Ratio (LMR), which will be recorded within 24 hours and on the 3rd day following a head injury. In addition, we will assess the comparative significance (hierarchy) of the SII index, NLR, PLR, and LMR in forecasting the prognosis of TBI patients. Over a period of 1 year, approximately 142 patients who match the specified inclusion criteria will be enrolled for the study. Patients will be treated following the established institutional protocol and recognized standards of care.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with moderate to severe head injury (GCS ≤12) Presented to the emergency ward within 24 hours of injury.
- •Patients with head injury findings on the first non-contrast computer tomography (NCCT) brain.
排除标准
- 未提供
结局指标
主要结局
To assess the predictive value of SII index for prognosis in Traumatic brain injury taking GOSE score of 5-8 as favourable prognosis.
时间窗: GOSE score will be assessed at discharge and at 3 months.
次要结局
- To compare and analyse the values of SII and NLR,PLR and LMR within 24 hours and 3rd day of head injury(first blood sample within 24 hours and 3rd day of admission.)
- To assess the order of importance(ranking) of SII index, NLR, PLR and LMR for prediction of TBI patients prognosis.(not applicable.)
研究者
aditya raj yadav
AIIMS Rishikesh