Sex differences in Social Cognition in Autism Spectrum Disorders (ASD)
- Conditions
- Autisme Spectrum StoornissenAutismAutism Spectrum Disorders10012562
- Registration Number
- NL-OMON49826
- Lead Sponsor
- Accare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 142
- Aged 12-17 at inclusion
- Ability to understand and speak Dutch
- Deemed reliable and compliant with the study protocol
- Be right-handed
Only for ASD participants:
- At least 14 days on stable medication
- Score of >60 on the SRS
• Intellectual disability (IQ < 70) based on available IQ measure or the
clinical opinion of the investigator (taking into account relevant psychosocial
information, e.g. educational level)
• History of or current head injury
• Genetic disorders associated with ASD (e.g. fragile X)
• Subject has known epilepsy
• Known lifetime history of a psychotic disorder or bipolar disorder, or
current severe mental state (e.g. depression)
Additional exclusion criteria for controls:
• A parent- or (where appropriate) self-reported diagnosis of a psychiatric
disorder.
• A score of > 60 on the parent-reported Social Responsiveness Scales (SRS)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The study parameters include questionnaires, neuropsychological tests,<br /><br>neurophysiological measurements during rest and neuropsychological computer<br /><br>tasks that evoke social cognition (assessed with electroencephalography [EEG]),<br /><br>and a clinical diagnostic assessment. The main study parameter is the<br /><br>difference in neurocognitive performance and neurophysiology between males and<br /><br>females with and without ASD.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Niet van toepassing</p><br>