Safety of Preoperative Carbohydrate Loading in Diabetic Patients
Completed
- Conditions
- Diabetes Mellitus Type 2Carbohydrate Intolerance
- Registration Number
- NCT04456166
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
The purpose of this study is to investigate the safety of preoperative carbohydrate loading in diabetic patients undergoing general anesthesia
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Elective surgery
- Type 2 diabetes mellitus on oral hypoglycemic agents
- American Society of Anesthesiologists physical status 2 or 3
- Ages 18 or more
- Approve to participate
Exclusion Criteria
- Ambulatory surgery
- BMI >35
- History of gastric or esophagus surgery
- History of GERD, dyspepesia or
- Anticipated difficult intubation (previous III or more Cormack and Lehane's grade, Mallamgrade, Mallampati scpati scoreore III or moreIII or more, propro/retro/retrognathism, gnathism, thyromental distance<6.5cm, thyromental distance<6.5cm, limited mouth openinglimited mouth opening)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Incidence of gastric ultrasonography score as low risk (grade 0 or 1) 30 minutes after intubation Ultrasound assessment of gastric volume by gastroscopic examination.
- Secondary Outcome Measures
Name Time Method The incidence of nausea and vomiting up to 30 minutes after extubation The incidence of insulin bolus injection up to 30 minutes after extubation Satisfaction scale of patients up to 30 minutes after extubation Gastric volume 30 minutes after intubation Blood sugar test 30 minutes after intubation and 30 minutes after extubation
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms explain preoperative carbohydrate loading's effect on glucose metabolism in Type 2 Diabetes patients during general anesthesia?
How does preoperative carbohydrate loading compare to traditional NPO protocols in perioperative glycemic control safety for diabetics?
Which biomarkers, such as HbA1c or C-peptide, predict optimal response to preoperative carbohydrate loading in Type 2 Diabetes patients undergoing surgery?
What adverse events are associated with preoperative carbohydrate loading in diabetic patients, and how are they managed during general anesthesia?
What preoperative nutritional strategies synergize with carbohydrate loading in diabetic patients undergoing general anesthesia, such as branched-chain amino acids or insulin sensitizers?
Trial Locations
- Locations (1)
Seoul National University Hospital
🇰🇷Seoul, Jongnogu, Korea, Republic of
Seoul National University Hospital🇰🇷Seoul, Jongnogu, Korea, Republic of