MedPath

Dexamethasone for PENG Block in Total Hip Arthroplasty

Phase 4
Completed
Conditions
Hip Osteoarthritis
Hip Arthropathy
Hip Pain Chronic
Interventions
Registration Number
NCT06470139
Lead Sponsor
Poznan University of Medical Sciences
Brief Summary

Effect of adding Dexamethasone to Periarticular Nerve Group Block in Patients undergoing Total Hip Arthroplasty

Detailed Description

Hip arthroplasty is one of the most common orthopaedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prostheses. Regional anaesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
60
Inclusion Criteria
  • patients scheduled for total hip arthroplasty
  • patients aged >65 and <100 years
  • patients able to provide informed consent
  • patients able to reliably report symptoms to the research team
Exclusion Criteria
  • inability to provide first-party consent due to cognitive impairment or a language barrier

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
RopivacaineRopivacaine 0.2% Injectable SolutionUltrasound-guided PENG block - 20ml 0,2% ropivacaine + 2ml 0.9% NaCl
Ropivacaine+DexamethasoneRopivacaine 0.2% Injectable Solution + 4mg DexamethasoneUltrasound-guided PENG block - 20ml 0,2% ropivacaine + 4mg Dexamethasone
Primary Outcome Measures
NameTimeMethod
Time to first rescue opioid analgesia48 hours after surgery

Time after surgery when the patient needs opiate for the first time

Secondary Outcome Measures
NameTimeMethod
Quadriceps muscle strength assessed using medical research council scale [range 0:5]48 hours after surgery

Quadriceps muscle strength (knee extension and hip adduction) will be evaluated according to the medical research council muscle strength rating

Nerve damage48 hours after surgery

Nerve damage assesent will be performed using scale: N0- no nerve damage; N1- minor - sensory paresthesia; N2- majorcomplete sensory anesthesia; N3- Complete- complete motor defect with or without paraesthesia; N4-CRPS- Complex Regional Pain Syndrome

glucose48 hours after surgery

blood glucose levels

Numerical Rating Scale [range 0:10]48 hours after surgery

Postoperative pain assessment will be performed using the NRS score (0 = no pain, 10 = the most severe pain felt)

Total Opioid Consumption48 hours after surgery

Total opiate consumption after surgery

Trial Locations

Locations (1)

Poznan University of Medical Sciences

🇵🇱

Poznan, Poznań, Poland

Poznan University of Medical Sciences
🇵🇱Poznan, Poznań, Poland

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