Pericapsular Nerve Group (PENG) Block Versus Periarticular Injection for Pain Management After Total Hip Arthroplasty

Not Applicable

Completed

• Conditions: Postoperative Pain; Total Hip Arthroplasty
• Interventions: Procedure: Pericapsular nerve group block; Procedure: Periarticular block

• Registration Number: NCT04981236
• Lead Sponsor: Yonsei University

Brief Summary

Adequate pain control after total hip arthroplasty is crucial for early ambulation and patient satisfaction. The pericapsular nerve group (PENG) block has been recently introduced a new technique for blockade of the articular branches of the femoral, obturator and accessory obturator nerves. PENG block provides sufficient analgesia but it is still the potential for quadriceps weakness that might delay ambulation. Periarticular injection has attached attention as an effective analgesic modality with a low prevalence of adverse effects. The investigators will compare ultrasound-guided PENG block with periarticular injection in patients undergoing total hip arthroplasty.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-07-22
• Study First Submitted QC: 2021-07-22
• Study First Posted: 2021-07-28
• Study Start: 2021-08-17
• Primary Completion: 2023-05-26
• Study Completion: 2023-05-26
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-13
• Last Update Posted: 2024-02-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

1. Aged 19 years old or older
2. American Society of Anesthesiologists Physical Status 1-3
3. Scheduled for elective unilateral total hip arthroplasty

Exclusion Criteria

1. Allergy or intolerance to any of the drugs used in the study
2. Hepatic or renal insufficiency
3. Opioid dependency
4. Coagulopathy
5. Pre-existing neurologic or anatomic deficits in the lower extremities
6. Severe psychiatric illness

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Pericapsular nerve group block	Pericapsular nerve group block	Participants receiving pericapsular nerve group block
Periarticular block	Periarticular block	Participants receiving periarticular block

Primary Outcome Measures

Name	Time	Method
Numeric rating scale pain score	at 24 hours postoperatively	Pain intensity at rest evaluated by an 11-point numeric rating scale (NRS: 0 = no pain, 10 = worst imaginable pain) at 24 hours postoperatively

Secondary Outcome Measures

Name	Time	Method
Numeric rating scale pain score	at 6 hours postoperatively and 48h postoperatively	Pain intensity at rest evaluated by an 11-point numeric rating scale (NRS: 0 = no pain, 10 = worst imaginable pain) at 6 hours postoperatively and 48h postoperatively
Quadriceps muscle strength	at 24 hours postoperatively	Quadriceps muscle strength will be measured by the dynamometer at 24h postoperatively

Trial Locations

Locations (1)

Division of Cardiac Anesthesiology, Department of Anesthesiology and Pain Medicine, Cardiovascular Hospital, Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; 🇰🇷 Seoul, Korea, Republic of