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Clinical Trials/NCT04336059
NCT04336059CompletedNot Applicable

Pericapsular Nerve Group Block in Hip Arthroplasty

Tanta University2 sites in 1 country50 target enrollmentStarted: May 1, 2020Last updated:
Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
50
Locations
2
Primary Endpoint
first time of rescue analgesia.

Study Overview

Brief Summary

Peripheral nerve blocks are becoming increasingly popular for hip surgery anesthesia. Modern regional anesthesia for major hip surgery includes the use of a single shot and continuous epidural or spinal injections, continuous lumbar plexus blockade and continuous peripheral blockade of the femoral nerve (FN), fascia iliaca (FI) block, 3-in-1 FN block and sciatic nerve. The use of either single shot or continuous peripheral nerve blocks are becoming increasingly popular.

This study will be conducted to evaluate the effect of ultrasound guided pericapsular nerve group block in hip arthroplasty surgery.

Detailed Description

Hip joint is richly innervated, and the pain following hip arthroplasty is particularly severe. Effective postoperative analgesic technique especially in an elderly with significant comorbidities is challenging. (1) Peripheral nerve blocks are becoming increasingly popular for hip surgery anesthesia. Modern regional anesthesia for major hip surgery includes the use of a single shot and continuous epidural or spinal injections, continuous lumbar plexus blockade and continuous peripheral blockade of the femoral nerve (FN), fascia iliaca (FI) block, 3-in-1 FN block and sciatic nerve. The use of either single shot or continuous peripheral nerve blocks are becoming increasingly popular. (2) These techniques have shown effective and safe postoperative pain control, resulting in lower opioid consumption, improved earlier rehabilitation and high patient satisfaction. (3) Pericapsular nerve group (PENG) block has been recently recommended by Giron-Arango et al. for use as postoperative analgesia in hip surgeries. It is a new regional anesthesia method based on blocking the articular branches of femoral nerve (FN) and accessory obturator nerve(AON) and obturator nerve in the region between the anterior inferior iliac spine (AIIS) and ilio-pubic eminence (IPE).The anterior capsule is the most richly innervated section of the joint suggesting these nerves should be the main targets for hip analgesia. (4)

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Supportive Care
Masking
Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)

Eligibility Criteria

Ages
50 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patients will involve in the research if they will schedule for unilateral hip arthroplasty (THA) surgery.
  • aged more than 50 years of both genders.
  • have American society of anesthiologists physical status I-II and III.

Exclusion Criteria

  • Revision hip arthroplasty.
  • hip arthroplasty. combined with subtrochanteric shortening osteotomy.
  • drug allergy.
  • regular narcotic use.
  • renal &/ or hepatic impairments.
  • coagulopathy disorders.

Outcomes

Primary Outcomes

first time of rescue analgesia.

Time Frame: postoperative first day

first time of rescue morphine analgesia.

Secondary Outcomes

  • postoperative morphine consumption(postoperative first day)
  • pain score(postoperative first day)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

tarek abdel hay mostafa

principle investigator

Tanta University

Study Sites (2)

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