Sperm DNA Damage to Intracytoplasmic Sperm Injection Outcome
Completed
- Conditions
- Infertility, Male
- Registration Number
- NCT03129243
- Lead Sponsor
- Assiut University
- Brief Summary
In the current era of assisted reproductive techniques where technology can help overcome defects in sperm function, the value of semen analysis has become even more inaccurate. Initial reports of intracytoplasmic sperm injection revealed its ability to bypass the natural selection process and enable men with severely impaired semen parameters to achieve both clinical pregnancy and live birth
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 120
Inclusion Criteria
- Infertile male patients with abnormal semen parameters.
- Normal female partner aged <38 years.
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Exclusion Criteria
- Female patients with obvious infertility factor.
- Male patients with azoospermia.
- Male patients with systemic diseases.
- Male patients receiving cytotoxic therapy.
- Male patients with genital pathology as cryptorchidism.
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Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method clinical pregnancy rate 4 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ahmed Abbas
🇪🇬Assiut, Cairo, Egypt