Evaluation of 3D DL oZTEo in the Detection of Osseous Changes in Patients With Inflammatory Arthritis
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- Mayo Clinic
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- The binary (yes/no) presence of bony erosions as detected by hand MRI with and without the addition of the 3D DL oZTEo sequence.
研究概览
简要总结
This project intends to explore and validate the utility of new MRI pulse sequence, 3D DL oZTEo, in the detection of osseous erosions of the hand in patients with inflammatory arthritis. The detection of osseous structural changes, such as erosive disease, is routinely assessed in patients with rheumatic conditions such as rheumatoid arthritis, as it alters clinical management, and in some cases assists in diagnosis. Currently, this is most often assessed with radiography and conventional MRI.
详细描述
This project intends to explore and validate the utility of new MRI pulse sequence, 3D DL oZTEo, in the detection of osseous erosions of the hand in patients with inflammatory arthritis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients ≥18 years of age
- •Hand radiographs performed within the past 3-6 months with imaging results available for analysis
- •Hand radiographs confirm the presence of bony erosions
- •Scheduled for a hand MRI as part of their routine clinical care at Mayo Clinic Rochester
排除标准
- •- Less than18 years of age
研究组 & 干预措施
oZTEo MRI pulse sequence
All patients will have the FDA approved MRI pulse sequence, oZTEo, added to their already ordered standard of care MRI examination.
干预措施: oZTEo (Device)
结局指标
主要结局
The binary (yes/no) presence of bony erosions as detected by hand MRI with and without the addition of the 3D DL oZTEo sequence.
时间窗: 1 day
The primary outcome
次要结局
- The number of erosions (continuous) as detected by hand MRI with and without the addition of the 3D DL oZTEo sequence.(1 day)
研究者
Naveen S. Murthy
Principal Investigator
Mayo Clinic