Osteoarthrosis on 7.0T Magnetic Resonance Imaging
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- The thickness of the cartilage of patellar on 7T MRI scan
研究概览
简要总结
This clinical trial studies the use of 7-Tesla (7T)and 3T magnetic resonance imaging (MRI) in detecting osteoarthrosis. 7T MRI has increased detection sensitivity, including more accurate lesion delineation, higher inter-rater agreement. Diagnostic procedures such as 7T MRI may help ultimately improved diagnostic and therapies confidence to inform decision making than standard 3T MRI.
详细描述
7T MRI increased detection sensitivity, attain superior anatomic resolution, higher spatial and spectral specificity of advanced quantitative techniques, and shorter scan times than 3T MRI. When applied clinically, these benefits translate to increased detection sensitivity, and ultimately improved diagnostic and therapies confidence to inform decision making. This study aim to detect the image characteristics and diagnostic accuracy of osteoarthrosis on 7T MRI.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age≥18 and ≤80
- •Having no contraindications against MRI
- •Clinically stable
排除标准
- •Age#18 or #80
- •Pregnancy and other contraindication to MRI scan
- •Informed consent not obtained
结局指标
主要结局
The thickness of the cartilage of patellar on 7T MRI scan
时间窗: baseline
Thickness of different part of the cartilage of patellar measured based on axial PD images
The T2 mapping value of the patellar cartilage on 7T MRI scan
时间窗: baseline
T2 relaxation times of the patellar cartilage measured based on T2 mapping
The abnormal signal in the infrapatellar fat pad
时间窗: baseline
The exist of abnormal signal in the infrapatellar fat pad detected based on sagittal PD images
次要结局
- Signal change of the patellar chondral before and after rehabilitation(1 month after rehabilitation)
- Signal change of the infrapatellar fat pad before and after rehabilitation(1 month after rehabilitation)
研究者
Xin Lou
Director and Clinical Professor
Chinese PLA General Hospital