A study to compare ultrasound-guided and transnasal sphenopalatine ganglion block for reducing pain after brain surgery in adults

Phase 3

Not yet recruiting

• Conditions: Medical and Surgical,

• Registration Number: CTRI/2025/06/089807

Brief Summary

This prospective randomized controlled trial is designed to compare the analgesic efficacy of ultrasound-guided bilateral sphenopalatine ganglion (SPG) block versus transnasal bilateral SPG block in adult patients undergoing supratentorial craniotomies. The primary objective is to evaluate postoperative pain using the Numeric Rating Scale (NRS). The study hypothesis is that ultrasound-guided SPG block provides superior postoperative analgesia compared to the transnasal technique. Secondary outcomes include time to first rescue analgesia and total analgesic consumption. The study is to be conducted at AIIMS Bathinda.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-06-29
• Study Start: 2025-09-08

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

• 1. Patients above 18 years of age of either gender.
• 2. American Society of Anaesthesiologists physical status I and II patients scheduled for elective craniotomy for supratentorial space-occupying lesions under general anesthesia 3) Pre-operative Glasgow Coma Scale 15.

Exclusion Criteria

• 1. Patients not giving consent.
• 2. Patients who are allergic to any study drug.
• 3. Patient with bleeding diathesis.
• 4. Patient with a history of facial trauma.
• 6. Patients not extubated immediately after surgery 7) History of nasal trauma, nasal bleed, nasal infection, nasal deformity 8) Neurosurgeries requiring pin application.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Postoperative pain will be assessed at 6, 12, 24, and 48 hours using the Numerical Rating Scale (NRS)	Postoperatively at 6, 12, 24, and 48 hours

Secondary Outcome Measures

Name	Time	Method
Intraoperative hemodynamic parameters (Heart rate, Systolic Blood pressure, Diastolic Blood pressure, Mean Arterial Pressure, SpO2)	0 minutes (baseline before incision),
Total post-operative analgesic consumption in 48 hours	48 hours postoperatively

Trial Locations

Locations (1)

All India Institute of Medical Sciences Bathinda; 🇮🇳 Bathinda, PUNJAB, India

All India Institute of Medical Sciences Bathinda

🇮🇳Bathinda, PUNJAB, India

Dr Chetan Kumar

Principal investigator

9988866777

ankuarora99@gmail.com