Transversus Abdominis Plane Block and Inguinal Hernia Repair

Not Applicable

Completed

• Conditions: Regional Anesthesia; Postoperative Pain; Abdominal Wall Muscles; Inguinal Hernia
• Interventions: Procedure: Transversus abdominis plane block

• Registration Number: NCT02030223
• Lead Sponsor: Papacharalampous Panagiota

Brief Summary

This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients undergoing unilateral inguinal hernia repair with a mesh under general anaesthesia, and how the efficiency of early postoperative analgesia achieved correlates with the risk of developing a chronic pain state, a not uncommon condition after this type of surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01
• Study First Submitted: 2014-01-07
• Study First Submitted QC: 2014-01-07
• Study First Posted: 2014-01-08
• Primary Completion: 2017-12
• Study Completion: 2017-12
• Status Verified: 2018-02
• Last Update Submitted: 2018-02-16
• Last Update Posted: 2018-02-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

ASA I-III patients undergoing inguinal hernia repair with a mesh

age between 18 and 75 years old

ability to read and write greek

Exclusion Criteria

• Inability to consent to the study
• BMI >40kg/m2
• Skin infection at the puncture site
• Contraindication to mono-amide local anaesthetics, paracetamol, NSAID's (parecoxib)
• Preoperative use of opioids or NSAID's for chronic pain conditions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Transversus abdominis plane block with 20 ml saline	Transversus abdominis plane block	Transversus abdominis plane block with 20 ml saline
Transversus abdominis plane block with 20 ml ropivacaine 0,75%	Transversus abdominis plane block	Transversus abdominis plane block with 20 ml ropivacaine 0,75%

Primary Outcome Measures

Name	Time	Method
Pain scores at rest and with movement using the numerical rating scale (NRS)	3, 6 and 24 hours postoperatively

Secondary Outcome Measures

Name	Time	Method
Incidence of chronic pain	6 months after surgery

Trial Locations

Locations (1)

Aretaieion University Hospital; 🇬🇷 Athens, Greece