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Clinical Trials/NCT04908878
NCT04908878CompletedNot Applicable

Analgesic Efficacy of Combined Ultrasound-Guided PECS II and Transeversus Thoracic Plane Blocks Versus Ultrasound-Guided Serratus Anterior Plane Block in Modified Radical Mastectomy: A Prospective Randomized Study

Tanta University2 sites in 1 country70 target enrollmentStarted: June 1, 2021Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Enrollment
70
Locations
2
Primary Endpoint
The total amount rescue analgesic consumption (morphine) in the first 24 hours postoperatively.
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

The aim of this study is to evaluate the analgesic efficacy of combined ultrasound (US)-guided pectoral nerve (PECS) block II and transversus thoracic plane (TTP) block versus US-guided serratus anterior plane (SAP) block in female patients undergoing modified radical mastectomy.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
Double (Participant, Outcomes Assessor)

Eligibility Criteria

Ages
21 Years to 60 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Female patients
  • •Aged 21-60 years
  • •ASA physical status I, II
  • •Scheduled for unilateral modified radical mastectomy

Exclusion Criteria

  • •Patient refusal.
  • •Known hypersensitivity to local anesthetics.
  • •Body mass index > 35 kg /m
  • •Uncooperative or psychiatric patients.
  • •Infection at the injection site.
  • •Coagulation disorder.

Outcomes

Primary Outcomes

The total amount rescue analgesic consumption (morphine) in the first 24 hours postoperatively.

Time Frame: First 24 hours postoperatively.

Rescue analgesia in the form of morphine (3mg IV) will be given if the VAS is ≥ 40, repeated with lock out interval of 5 min guided with the occurrence of complications till the VAS is decreased to less than 40.

Secondary Outcomes

  • The degree of postoperative pain(First 24 hours postoperatively.)
  • Intraoperative fentanyl consumption.(Intraoperative)
  • Time to first rescue analgesia request.(First 24 hours postoperatively.)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Alshaimaa Soliman Alasrag

Resident at Anesthesiology, Surgical ICU and Pain medicine

Tanta University

Study Sites (2)

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