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Clinical Trials/NCT05323305
NCT05323305
Unknown
Not Applicable

Ultrasound Guided Pectointercostal Fascial Plane Block Versus Transversus Thoracic Plane Block In Adult Cardiac Surgery Patients: A Comparative Study

Alexandria University1 site in 1 country60 target enrollmentMarch 30, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Pain, Post Operative
Sponsor
Alexandria University
Enrollment
60
Locations
1
Primary Endpoint
the analgesic effectiveness of the two blocks on midline sternotomy pain,
Last Updated
4 years ago

Overview

Brief Summary

The study will be designed to compare the analgesic effect of ultrasound-guided pectointercostal fascial plane block versus tansversus thoracic plane block in adult cardiac surgery.

Detailed Description

A prospective study will be carried out in Alexandria Main University Hospitals on 60 adult patients planned for elective cardiac surgery, after approval of the Ethical Committee of Faculty of Medicine, Alexandria, and having an informed written consent taken from patients included in the study. Patients will be categorized into two equal groups; group P (n=30)) will receive ultrasound-guided pectointercostal fascial plane block and group T (n=30) will receive ultrasound-guided transversus thoracic plane block. All patients will receive the ultrasound-guided block after induction of anesthesia and an equal booster dose of the same block before extubation in the ICU. Patients in both groups will also receive an ultrasound-guided bilateral serratus anterior plane block before extubation.

Registry
clinicaltrials.gov
Start Date
March 30, 2022
End Date
December 2022
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult patient.
  • Elective cardiac surgery.

Exclusion Criteria

  • Refusal to participate.
  • Redo or urgent cardiac surgery.
  • Local infection of the skin at the site of needle puncture.
  • Allergy to bupivacaine.
  • Coagulation disorders.
  • Clinically significant liver or kidney disease, heart failure, moderate to severe pulmonary hypertension.
  • when extubation is intentionally planned to be delayed

Outcomes

Primary Outcomes

the analgesic effectiveness of the two blocks on midline sternotomy pain,

Time Frame: from end of surgery till discharge from ICU (96 hours)

Postoperative pain evaluation after extubation will be done using the Visual Analogue Scale (VAS). a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between 0 "no pain" and 10 "worst pain."

Secondary Outcomes

  • length of stay in ICU(average 4 days)
  • pulmonary complications(from end of surgery till discharge from ICU (96 hours))

Study Sites (1)

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